Rome2Rio

Madrid to Rome trains

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Trip Overview

The average train between Madrid and Rome takes 46h 52m and the fastest train takes 36h 59m. The train runs, on average, 2 times per week from Madrid to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

46h 52m
Duration
2,290 km
Distance
€320
Average price
Twice a week
Frequency

Madrid to Rome train times

Trains run twice a week between Madrid and Rome. The earliest departure is at 12:33 AM at night, and the last departure from Madrid is at 8:20 PM which arrives into Rome at 9:19 AM. All services require a transfer at Madrid-Atocha Cercanías and take an average of 46h 52m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe AVERenfe ViajerosTrenitaliaItaloTreno36h 59m • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Renfe CercaniasRenfe AVERenfe ViajerosTrenitaliaItaloTreno2d 8h • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Rome.ExpandLaunch map view
  • Distance: 2,290 km
  • Duration: 46h 52m

What companies run services between Madrid, Spain and Rome, Italy?

You can take a train from Sol to Roma Termini via Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, Lyon Part Dieu, and Milano Centrale in around 18h 24m.

Operators