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Madrid to Brindisi trains

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Trip Overview

The average train between Madrid and Brindisi takes 47h 30m and the fastest train takes 45h 54m. The train runs, on average, 5 times per week from Madrid to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

47h 30m
Duration
2,615 km
Distance
€466
Average price
5 times a week
Frequency

Madrid to Brindisi train times

Trains run 5 times a week between Madrid and Brindisi. The earliest departure is at 12:50 PM in the afternoon, and the last departure from Madrid is at 8:30 PM which arrives into Brindisi at 6:24 PM. All services require a transfer at Barcelona-Sants and take an average of 47h 30m. The schedules shown below are for the next available departures.

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Wednesday, October 14, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Thursday, October 15, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Friday, October 16, 2026

  •  → 

    Arrives +2 days

    Renfe ViajerosTGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce2d 5h • 4 changes

Departing Saturday, October 17, 2026

  •  → 

    Arrives +2 days

    OuigoTGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce46h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Brindisi.ExpandLaunch map view
  • Distance: 2,614.7 km
  • Duration: 47h 30m

What companies run services between Madrid, Spain and Brindisi, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Brindisi via Barcelona-Sants, Valence Tgv Rhone-Alpes Sud, Chambery Challes Les Eaux, and Torino Porta Susa in around 24h 27m.

Operators