Rome2Rio

Madrid to Brindisi trains

Find Transport to Brindisi

View schedule

Trip Overview

The train between Madrid and Brindisi takes 45h 54m. The train runs, on average, 5 times per week from Madrid to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 54m
Duration
2,615 km
Distance
€462
Average price
5 times a week
Frequency

Madrid to Brindisi train times

Trains run 5 times a week between Madrid and Brindisi. The service departs Madrid at 8:30 PM in the evening, which arrives into Brindisi at 18:24:00. All services require a transfer at Barcelona-Sants and take an average of 45h 54m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Monday, October 26, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Tuesday, October 27, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Wednesday, October 28, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Departing Thursday, October 29, 2026

  •  → 

    Arrives +2 days

    Renfe AVETGV inOuiZou! Lignes Express RégionalesTrenitaliaTrenitalia Frecce45h 54m • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Brindisi.ExpandLaunch map view
  • Distance: 2,614.7 km
  • Duration: 45h 54m

What companies run services between Madrid, Spain and Brindisi, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Brindisi via Barcelona-Sants, Valence Tgv Rhone-Alpes Sud, Chambery Challes Les Eaux, and Torino Porta Susa in around 24h 30m.

Operators