The average train between Madrid and Cartagena takes 5h 42m and the fastest train takes 4h 18m. The train service runs several times per day from Madrid to Cartagena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Madrid and Cartagena. The earliest departure is at 6:15 AM in the morning, and the last departure from Madrid is at 7:15 PM which arrives into Cartagena at 8:25 AM. All services require a transfer, and take on average 5h 42m. The schedules shown below are for the next available departures.

5h 1m • 1 change

4h 49m • 1 change

4h 18m • 1 change

4h 19m • 1 change

5h 1m • 1 change

4h 18m • 1 change

4h 19m • 1 change
Arrives next day

13h 10m • 1 change

5h 1m • 1 change

4h 49m • 1 change

4h 18m • 1 change

4h 19m • 1 change

5h 1m • 1 change

4h 49m • 1 change

4h 18m • 1 change

4h 19m • 1 change

5h 1m • 1 change

4h 49m • 1 change

4h 18m • 1 change

4h 19m • 1 change
Want to know about travelling from Madrid to Cartagena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Madrid to Cartagena. However, there are services departing from Madrid station and arriving at Cartagena station via Murcia Del Carmen. The journey, including transfers, takes approximately 5h 42m.
Madrid to Cartagena train services, operated by Renfe AVE, depart from Madrid Chamartín station.
Madrid to Cartagena train services, operated by Renfe AVE, arrive at Cartagena station.
Book your Madrid to Cartagena train tickets online with Renfe AVE, Renfe Viajeros and Ouigo.
The distance between Madrid and Cartagena is 390.9 km. The road distance is 559 km.
You can take a train from Madrid Chamartín to Cartagena via Murcia Del Carmen in around 4h 40m.