Rome2Rio

Madrid to Lake Iseo trains

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Trip Overview

The average train between Madrid and Lake Iseo takes 36h 12m and the fastest train takes 36h 7m. The train runs, on average, 4 times per week from Madrid to Lake Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 12m
Duration
1,821 km
Distance
€258
Average price
4 times a week
Frequency

Madrid to Lake Iseo train times

Trains run 4 times a week between Madrid and Lake Iseo. The earliest departure is at 8:10 PM in the evening, and the last departure from Madrid is at 8:30 PM which arrives into Lake Iseo at 8:37 AM. All services require a transfer at Barcelona-Sants and take an average of 36h 12m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    OuigoRenfe ViajerosTrenitaliaTrenitalia FrecceTrenord36h 27m • 4 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaTrenitalia FrecceTrenord36h 7m • 4 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaTrenitalia FrecceTrenord36h 7m • 4 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaTrenitalia FrecceTrenord36h 7m • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Lake Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Lake Iseo.ExpandLaunch map view
  • Distance: 1,821.2 km
  • Duration: 36h 12m

What companies run services between Madrid, Spain and Lake Iseo, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Sulzano via Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Brescia in around 17h 22m.

Operators