The average train between Madrid and Osuna takes 5h 59m and the fastest train takes 3h 39m. The train service runs several times per day from Madrid to Osuna. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Madrid and Osuna. The earliest departure is at 7:20 AM in the morning, and the last departure from Madrid is at 8:35 PM which arrives into Osuna at 9:01 AM. All services require a transfer, and take on average 5h 59m. The schedules shown below are for the next available departures.

3h 53m • 1 change

4h 54m • 1 change

3h 39m • 1 change
Arrives next day

12h 26m • 1 change

3h 53m • 1 change

4h 54m • 1 change

3h 39m • 1 change
Arrives next day

12h 26m • 1 change

3h 53m • 1 change

4h 54m • 1 change

3h 39m • 1 change
Arrives next day

12h 26m • 1 change

3h 53m • 1 change

4h 54m • 1 change

3h 39m • 1 change
Arrives next day

12h 26m • 1 change

3h 53m • 1 change

4h 54m • 1 change

3h 39m • 1 change
Arrives next day

12h 26m • 1 change
Want to know about travelling from Madrid to Osuna? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Madrid to Osuna. However, there are services departing from Madrid station and arriving at Osuna station via Antequera-Santa Ana. The journey, including transfers, takes approximately 5h 59m.
Madrid to Osuna train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
Madrid to Osuna train services, operated by Renfe AVE, arrive at Osuna station.
Book your Madrid to Osuna train tickets online with Renfe AVE and Renfe Viajeros.
The distance between Madrid and Osuna is 373.7 km. The road distance is 503 km.
You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Osuna via Antequera-Santa Ana in around 4h 8m.