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Madrid to Palermo trains

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Trip Overview

The train between Madrid and Palermo takes 2d 2h. The train runs, on average, 5 times per week from Madrid to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 2h
Duration
3,154 km
Distance
€435
Average price
5 times a week
Frequency

Madrid to Palermo train times

Trains run 5 times a week between Madrid and Palermo. The service departs Madrid at 8:30 PM in the evening, which arrives into Palermo at 22:58:00. All services require a transfer at Barcelona-Sants and take an average of 2d 2h. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTrenoTrenitalia Intercity2d 2h • 4 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTrenoTrenitalia Intercity2d 2h • 4 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTrenoTrenitalia Intercity2d 2h • 4 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTrenoTrenitalia Intercity2d 2h • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Renfe AVERenfe ViajerosTrenitaliaItaloTrenoTrenitalia Intercity2d 3h • 4 changes

Frequently asked questions

Want to know about travelling from Madrid to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Palermo.ExpandLaunch map view
  • Distance: 3,153.7 km
  • Duration: 2d 2h

What companies run services between Madrid, Spain and Palermo, Italy?

You can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Palermo Centrale via Barcelona-Sants, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 30h 44m.

Operators