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Mainz, Hauptbahnhof to Amsterdam trains

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Trip Overview

The average train between Mainz, Hauptbahnhof and Amsterdam takes 4h 34m and the fastest train takes 4h 19m. The train service runs several times per day from Mainz, Hauptbahnhof to Amsterdam. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 34m
Duration
454 km
Distance
€64
Average price
4 times a day
Frequency

Mainz, Hauptbahnhof to Amsterdam train times

Trains run 4 times a day between Mainz, Hauptbahnhof and Amsterdam. The earliest departure is at 5:06 AM in the morning, and the last departure from Mainz, Hauptbahnhof is at 7:10 PM which arrives into Amsterdam at 11:54 PM. All services require a transfer at Frankfurt and take an average of 4h 34m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change

Departing Friday, November 13, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change

Departing Saturday, November 14, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change

Departing Sunday, November 15, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change

Departing Monday, November 16, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 48m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 44m • 1 change

Departing Tuesday, November 17, 2026

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    vlexxNederlandse Spoorwegen (NS)4h 26m • 1 change
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    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  • Show more

Departing Wednesday, November 18, 2026

  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 26m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  •  → 

    vlexxNederlandse Spoorwegen (NS)4h 19m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Mainz, Hauptbahnhof to Amsterdam? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz, Hauptbahnhof to Amsterdam.ExpandLaunch map view
  • Distance: 454.1 km
  • Duration: 4h 34m

What companies run services between Mainz, Hauptbahnhof, Germany and Amsterdam, Netherlands?

Nederlandse Spoorwegen (NS) operates a train from Frankfurt Flughafen Fernb to Amsterdam Centraal every 4 hours. Tickets cost €45–90 and the journey takes 3h 41m.

Operators