The average train between Mainz, Hauptbahnhof and Berlin takes 5h 40m and the fastest train takes 4h 48m. There is a train service every few hours from Mainz, Hauptbahnhof to Berlin. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz, Hauptbahnhof and Berlin. The earliest departure is at 4:57 AM at night, and the last departure from Mainz, Hauptbahnhof is at 10:42 PM which arrives into Berlin at 5:56 AM. All services require a transfer, and take on average 5h 40m. The schedules shown below are for the next available departures.

5h 36m • 1 change
4h 48m • 1 change
5h 8m • 1 change
4h 50m • 1 change
5h 36m • 1 change
4h 48m • 1 change
5h 37m • 1 change
5h 35m • 1 change
5h 36m • 1 change
4h 48m • 1 change
5h 37m • 1 change
5h 35m • 1 change
5h 36m • 1 change
4h 48m • 1 change
5h 8m • 1 change
4h 50m • 1 change
5h 36m • 1 change
4h 48m • 1 change
5h 8m • 1 change
4h 50m • 1 changeWant to know about travelling from Mainz, Hauptbahnhof to Berlin? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz, Hauptbahnhof to Berlin. However, there are services departing from Mainz, Hauptbahnhof station and arriving at Berlin station via Berlin Hbf. The journey, including transfers, takes approximately 5h 40m.
Mainz, Hauptbahnhof to Berlin train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz, Hauptbahnhof to Berlin train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Berlin Hbf station.
Book your Mainz, Hauptbahnhof to Berlin train tickets online with Deutsche Bahn Intercity (DB IC) and vlexx.
The distance between Mainz, Hauptbahnhof and Berlin is 455 km. The road distance is 548 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Berlin Hbf hourly. Tickets cost €95–190 and the journey takes 4h 2m.