Mainz, Hauptbahnhof to Brussels Trains

Mainz, Hauptbahnhof to Brussels trains

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Trip Overview

The average train between Mainz, Hauptbahnhof and Brussels takes 4h 39m and the fastest train takes 4h 15m. The train service runs several times per day from Mainz, Hauptbahnhof to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 39m
Duration: 401 km
Distance: €99
Average price: Every 4 hours
Frequency

Train via Cologne

best

Take the train from Mainz, Hauptbahnhof to Köln Hbftrain 91 / ...
Take the train from Köln Hbf to Bruxelles Miditrain 79

4h 27m

€55–194

Mainz, Hauptbahnhof to Brussels train times

Trains run every 4 hours between Mainz, Hauptbahnhof and Brussels. The earliest departure is at 3:49 AM at night, and the last departure from Mainz, Hauptbahnhof is at 7:20 PM which arrives into Brussels at 11:35 PM. All services require a transfer, and take on average 4h 39m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

2:19 PM → 7:35 PM
5h 16m • 1 change
5:20 PM → 9:35 PM
4h 15m • 1 change
7:20 PM → 11:35 PM
4h 15m • 1 change

Departing Sunday, October 11, 2026

3:49 AM → 9:35 AM
5h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Departing Monday, October 12, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Departing Tuesday, October 13, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Departing Wednesday, October 14, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Departing Thursday, October 15, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Departing Friday, October 16, 2026

3:49 AM → 8:35 AM
4h 46m • 1 change
7:17 AM → 11:35 AM
4h 18m • 1 change
9:20 AM → 1:35 PM
4h 15m • 1 change
10:02 AM → 3:35 PM
5h 33m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Mainz, Hauptbahnhof to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Mainz, Hauptbahnhof to Brussels trains

Find Transport to Brussels

Trip Overview

Train via Cologne

Mainz, Hauptbahnhof to Brussels train times

Departing Saturday, October 10, 2026

2:19 PM → 7:35 PM

5:20 PM → 9:35 PM

7:20 PM → 11:35 PM

Departing Sunday, October 11, 2026

3:49 AM → 9:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Departing Monday, October 12, 2026

3:49 AM → 8:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Departing Tuesday, October 13, 2026

3:49 AM → 8:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Departing Wednesday, October 14, 2026

3:49 AM → 8:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Departing Thursday, October 15, 2026

3:49 AM → 8:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Departing Friday, October 16, 2026

3:49 AM → 8:35 AM

7:17 AM → 11:35 AM

9:20 AM → 1:35 PM

10:02 AM → 3:35 PM

Frequently asked questions

What companies run services between Mainz, Hauptbahnhof, Germany and Brussels, Belgium?

Train from Mainz, Hauptbahnhof to Köln Hbf

Train from Köln Hbf to Bruxelles Midi

Where to next?

Train trips from Mainz, Hauptbahnhof

Train trips to Brussels

Alternative transport options