Mainz, Hauptbahnhof to Milan Trains

Mainz, Hauptbahnhof to Milan trains

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Trip Overview

The average train between Mainz, Hauptbahnhof and Milan takes 9h 25m and the fastest train takes 7h 31m. The train service runs several times per day from Mainz, Hauptbahnhof to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 25m
Duration: 652 km
Distance: €172
Average price: Every 4 hours
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain

9h 14m

€77–292

Mainz, Hauptbahnhof to Milan train times

Trains run every 4 hours between Mainz, Hauptbahnhof and Milan. The earliest departure is at 1:38 AM at night, and the last departure from Mainz, Hauptbahnhof is at 11:08 PM which arrives into Milan at 11:17 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 9h 25m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
1:13 PM → 9:17 PM
8h 4m • 3 changes
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Departing Friday, October 16, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Saturday, October 17, 2026

1:38 AM → 11:17 AM
9h 39m • 3 changes
5:40 AM → 1:17 PM
7h 37m • 3 changes
6:56 AM → 3:17 PM
8h 21m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
Show more

Departing Sunday, October 18, 2026

1:38 AM → 11:17 AM
9h 39m • 3 changes
5:40 AM → 1:17 PM
7h 37m • 3 changes
6:56 AM → 3:17 PM
8h 21m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
Show more

Departing Monday, October 19, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Tuesday, October 20, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Departing Wednesday, October 21, 2026

5:40 AM → 1:17 PM
7h 37m • 3 changes
7:46 AM → 3:17 PM
7h 31m • 3 changes
9:13 AM → 5:17 PM
8h 4m • 3 changes
11:17 AM → 7:17 PM
8h • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Mainz, Hauptbahnhof to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.