The average train between Mainz, Hauptbahnhof and Strasbourg takes 2h 28m and the fastest train takes 2h 6m. The train service runs several times per day from Mainz, Hauptbahnhof to Strasbourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Mainz, Hauptbahnhof and Strasbourg. The earliest departure is at 5:52 AM in the morning, and the last departure from Mainz, Hauptbahnhof is at 4:42 PM which arrives into Strasbourg at 6:48 PM. All services require a transfer, and take on average 2h 28m. The schedules shown below are for the next available departures.

2h 55m • 1 change
2h 9m • 1 change
2h 52m • 1 change
2h 6m • 1 change
2h 55m • 1 change
2h 9m • 1 change
2h 52m • 1 change
2h 6m • 1 changeWant to know about travelling from Mainz, Hauptbahnhof to Strasbourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz, Hauptbahnhof to Strasbourg. However, there are services departing from Mainz, Hauptbahnhof station and arriving at Strasbourg station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 2h 28m.
Mainz, Hauptbahnhof to Strasbourg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz, Hauptbahnhof to Strasbourg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Book your Mainz, Hauptbahnhof to Strasbourg train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Süwex.
The distance between Mainz, Hauptbahnhof and Strasbourg is 161.9 km. The road distance is 212 km.
You can take a train from Mainz, Hauptbahnhof to Strasbourg Bahnhof via Mannheim, Hauptbahnhof in around 2h 48m.