The average train between Mainz, Hauptbahnhof and Zurich takes 5h 5m and the fastest train takes 4h 14m. There is an hourly train service from Mainz, Hauptbahnhof to Zurich. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz, Hauptbahnhof and Zurich. The earliest departure is at 1:38 AM at night, and the last departure from Mainz, Hauptbahnhof is at 11:08 PM which arrives into Zurich at 7:26 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 5h 5m. The schedules shown below are for the next available departures.


6h 43m • 2 changes

4h 20m • 2 changes

5h 32m • 2 changes

4h 14m • 2 changes

6h 43m • 2 changes

4h 20m • 2 changes

5h 32m • 2 changes

4h 14m • 2 changes

5h 48m • 2 changes

4h 20m • 2 changes

5h 4m • 2 changes

4h 42m • 2 changesWant to know about travelling from Mainz, Hauptbahnhof to Zurich? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz, Hauptbahnhof to Zurich. However, there are services departing from Mainz, Hauptbahnhof station and arriving at Zurich station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 5h 5m.
Mainz, Hauptbahnhof to Zurich train services, operated by Nederlandse Spoorwegen (NS), depart from Mainz, Hauptbahnhof station.
Mainz, Hauptbahnhof to Zurich train services, operated by Nederlandse Spoorwegen (NS), arrive at Zürich HB station.
Book your Mainz, Hauptbahnhof to Zurich train tickets online with Nederlandse Spoorwegen (NS), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz, Hauptbahnhof and Zurich is 293.7 km. The road distance is 411 km.
You can take a train from Mainz, Hauptbahnhof to Zürich HB via Mannheim, Hauptbahnhof and Basel SBB in around 4h 45m.