The average train between Mainz and Amsterdam takes 6h 9m and the fastest train takes 4h 15m. The train service runs several times per day from Mainz to Amsterdam. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Mainz and Amsterdam. The earliest departure is at 9:14 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Amsterdam at 8:59 AM. All services require a transfer at Frankfurt and take an average of 6h 9m. The schedules shown below are for the next available departures.
Arrives next day


11h 45m • 2 changes
Arrives next day


10h 14m • 2 changes


4h 15m • 2 changes


4h 15m • 2 changes


4h 15m • 2 changes


6h 15m • 2 changes
Want to know about travelling from Mainz to Amsterdam? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Amsterdam. However, there are services departing from Mainz station and arriving at Amsterdam station via Düsseldorf Hbf. The journey, including transfers, takes approximately 6h 9m.
Mainz to Amsterdam train services, operated by vlexx, depart from Frankfurt station.
Mainz to Amsterdam train services, operated by vlexx, arrive at Amsterdam Centraal station.
Book your Mainz to Amsterdam train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and Nederlandse Spoorwegen (NS).
The distance between Mainz and Amsterdam is 355.5 km. The road distance is 450 km.
You can take a train from Mainz, Römisches Theater to Amsterdam Centraal via Frankfurt and Düsseldorf Hbf in around 5h 5m.