The average train between Mainz and Berlin Hbf takes 5h 28m and the fastest train takes 4h 40m. The train service runs several times per day from Mainz to Berlin Hbf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mainz and Berlin Hbf. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Berlin Hbf at 8:06 AM. All services require a transfer, and take on average 5h 28m. The schedules shown below are for the next available departures.

4h 47m • 1 change

5h 16m • 1 change
Arrives next day

5h 16m • 1 change
Arrives next day

9h 45m • 1 change

5h 21m • 1 change

4h 48m • 1 change

4h 40m • 1 change

5h 16m • 1 change

5h 21m • 1 change

4h 48m • 1 change

4h 40m • 1 change

5h 16m • 1 change

5h 16m • 1 change

4h 47m • 1 change

5h 16m • 1 change

4h 47m • 1 change

5h 16m • 1 change

4h 47m • 1 change

5h 16m • 1 change

4h 47m • 1 change

5h 21m • 1 change

4h 48m • 1 change

4h 40m • 1 change

5h 16m • 1 change
Want to know about travelling from Mainz to Berlin Hbf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Berlin Hbf. However, there are services departing from Mainz station and arriving at Berlin Hbf station via Berlin Hbf. The journey, including transfers, takes approximately 5h 28m.
Mainz to Berlin Hbf train services, operated by vlexx, depart from Frankfurt station.
Mainz to Berlin Hbf train services, operated by vlexx, arrive at Berlin Hbf station.
The distance between Mainz and Berlin Hbf is 452.9 km. The road distance is 549 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Berlin Hbf hourly. Tickets cost €90–410 and the journey takes 4h 2m.