The average train between Mainz and Brindisi takes 24h 23m and the fastest train takes 19h 51m. The train service runs several times per day from Mainz to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mainz and Brindisi. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Brindisi at 9:29 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 24h 23m. The schedules shown below are for the next available departures.
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26h 52m • 5 changes
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25h 31m • 5 changes
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22h 21m • 5 changes
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26h 52m • 5 changes
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25h 31m • 5 changes
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22h 21m • 5 changes
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26h 15m • 5 changes
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21h 42m • 5 changes
Want to know about travelling from Mainz to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Brindisi. However, there are services departing from Mainz station and arriving at Brindisi station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 24h 23m.
Mainz to Brindisi train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Hauptbahnhof station.
Mainz to Brindisi train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brindisi station.
Book your Mainz to Brindisi train tickets online with Deutsche Bahn Regio (DB Regional), Nederlandse Spoorwegen (NS) and 5 other operators.
The distance between Mainz and Brindisi is 1,282.9 km. The road distance is 1,620 km.
You can take a train from Mainz, Hauptbahnhof to Brindisi via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 18h 39m.