The average train between Mainz and Darmstadt takes 1h 10m and the fastest train takes 1h 4m. There is a train service every few hours from Mainz to Darmstadt. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Darmstadt. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Darmstadt at 12:25 AM. All services require a transfer, and take on average 1h 10m. The schedules shown below are for the next available departures.

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1h 11m • 1 change

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1h 11m • 1 change
Want to know about travelling from Mainz to Darmstadt? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Darmstadt. However, there are services departing from Mainz station and arriving at Darmstadt station via Frankfurt. The journey, including transfers, takes approximately 1h 10m.
Mainz to Darmstadt train services, operated by vlexx, depart from Mainz, Römisches Theater station.
Mainz to Darmstadt train services, operated by vlexx, arrive at Darmstadt Hauptbahnhof station.
Book your Mainz to Darmstadt train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Mainz and Darmstadt is 29.4 km. The road distance is 65 km.
You can take a train from Mainz, Römisches Theater to Darmstadt Hauptbahnhof via Frankfurt in around 1h 7m.