The average train between Mainz and Dortmund takes 3h 20m and the fastest train takes 2h 33m. The train service runs several times per day from Mainz to Dortmund. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mainz and Dortmund. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Dortmund at 9:21 AM. All services require a transfer, and take on average 3h 20m. The schedules shown below are for the next available departures.

4h 12m • 1 change

2h 34m • 1 change

2h 51m • 1 change

2h 33m • 1 change

4h 12m • 1 change

2h 34m • 1 change

2h 51m • 1 change

2h 33m • 1 change

4h 12m • 1 change

2h 34m • 1 change

2h 51m • 1 change

2h 33m • 1 change

4h 12m • 1 change

2h 34m • 1 change

2h 51m • 1 change

2h 33m • 1 change

2h 36m • 1 change

2h 36m • 1 change

2h 36m • 1 change

2h 36m • 1 change
Want to know about travelling from Mainz to Dortmund? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Dortmund. However, there are services departing from Mainz station and arriving at Dortmund station via Dortmund Hbf. The journey, including transfers, takes approximately 3h 20m.
Mainz to Dortmund train services, operated by vlexx, depart from Frankfurt station.
Mainz to Dortmund train services, operated by vlexx, arrive at Dortmund Hbf station.
Book your Mainz to Dortmund train tickets online with vlexx and Deutsche Bahn Intercity (DB IC).
The distance between Mainz and Dortmund is 179.6 km. The road distance is 311 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Dortmund Hbf hourly. Tickets cost €50–230 and the journey takes 2h 9m.