The average train between Mainz and Duisburg takes 2h 26m and the fastest train takes 1h 54m. There is a train service every few hours from Mainz to Duisburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Duisburg. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 11:14 PM which arrives into Duisburg at 2:49 AM. All services require a transfer, and take on average 2h 26m. The schedules shown below are for the next available departures.
Arrives next day

3h 34m • 1 change
Arrives next day

3h 35m • 1 change

2h 10m • 1 change

1h 55m • 1 change

1h 55m • 1 change

1h 55m • 1 change

2h 15m • 1 change

1h 56m • 1 change

1h 55m • 1 change

1h 55m • 1 change

2h 15m • 1 change

1h 56m • 1 change

1h 55m • 1 change

1h 55m • 1 change

2h 41m • 1 change

2h 15m • 1 change

1h 56m • 1 change

1h 58m • 1 change
Want to know about travelling from Mainz to Duisburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Duisburg. However, there are services departing from Mainz station and arriving at Duisburg station via Frankfurt. The journey, including transfers, takes approximately 2h 26m.
Mainz to Duisburg train services, operated by vlexx, depart from Mainz, Römisches Theater station.
Mainz to Duisburg train services, operated by vlexx, arrive at Duisburg Hbf station.
Book your Mainz to Duisburg train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Duisburg is 193.1 km. The road distance is 256 km.
You can take a train from Mainz, Römisches Theater to Duisburg Hbf via Frankfurt in around 2h 8m.