The average train between Mainz and Eisenach takes 2h 44m and the fastest train takes 2h 33m. There is a train service every few hours from Mainz to Eisenach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Eisenach. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 10:16 PM which arrives into Eisenach at 5:20 AM. All services require a transfer, and take on average 2h 44m. The schedules shown below are for the next available departures.

3h 16m • 1 change
2h 52m • 1 change
2h 34m • 1 change
2h 48m • 1 change
3h 16m • 1 change
2h 52m • 1 change
2h 34m • 1 change
2h 48m • 1 change
2h 52m • 1 change
2h 34m • 1 change
2h 48m • 1 change
2h 34m • 1 changeWant to know about travelling from Mainz to Eisenach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Eisenach. However, there are services departing from Mainz station and arriving at Eisenach station via Frankfurt. The journey, including transfers, takes approximately 2h 44m.
Mainz to Eisenach train services, operated by vlexx, depart from Mainz, Römisches Theater station.
Mainz to Eisenach train services, operated by vlexx, arrive at Eisenach Hbf station.
Book your Mainz to Eisenach train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mainz and Eisenach is 181.7 km. The road distance is 237 km.
You can take a train from Mainz, Römisches Theater to Eisenach Hbf via Frankfurt in around 3h 10m.