Mainz to Florence Trains

Mainz to Florence trains

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Mainz to Florence train times

Trains run 5 times a day between Mainz and Florence. The earliest departure is at 7:05 AM in the morning, and the last departure from Mainz is at 9:14 PM which arrives into Florence at 11:35 AM. All services require a transfer at Frankfurt and take an average of 14h 39m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

7:14 PM → 1:35 PM
Arrives next day
18h 21m • 4 changes

Departing Thursday, November 5, 2026

7:13 AM → 5:35 PM
10h 22m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes
1:14 PM → 7:35 AM
Arrives next day
18h 21m • 4 changes
5:14 PM → 9:35 AM
Arrives next day
16h 21m • 4 changes
Show more

Departing Friday, November 6, 2026

7:13 AM → 5:35 PM
10h 22m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes
1:14 PM → 7:35 AM
Arrives next day
18h 21m • 4 changes
5:14 PM → 9:35 AM
Arrives next day
16h 21m • 4 changes
Show more

Departing Saturday, November 7, 2026

7:05 AM → 5:35 PM
10h 30m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes
1:14 PM → 7:35 AM
Arrives next day
18h 21m • 4 changes
5:14 PM → 9:35 AM
Arrives next day
16h 21m • 4 changes
Show more

Departing Sunday, November 8, 2026

7:05 AM → 5:35 PM
10h 30m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes
1:14 PM → 7:35 AM
Arrives next day
18h 21m • 4 changes
5:14 PM → 9:35 AM
Arrives next day
16h 21m • 4 changes
Show more

Departing Monday, November 9, 2026

7:13 AM → 5:35 PM
10h 22m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes
1:14 PM → 7:35 AM
Arrives next day
18h 21m • 4 changes
5:14 PM → 9:35 AM
Arrives next day
16h 21m • 4 changes
Show more

Departing Tuesday, November 10, 2026

7:13 AM → 5:35 PM
10h 22m • 4 changes
9:14 AM → 7:35 PM
10h 21m • 4 changes

Frequently asked questions

Want to know about travelling from Mainz to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Mainz, Germany and Florence, Italy?

You can take a train from Mainz, Römisches Theater to Firenze Santa Maria Novella via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 12h 17m.

Operators