The average train between Mainz and Italy takes 14h 48m and the fastest train takes 11h 33m. The train service runs several times per day from Mainz to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Italy. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Italy at 3:19 PM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 14h 48m. The schedules shown below are for the next available departures.




11h 33m • 4 changes



11h 52m • 4 changes



12h 7m • 4 changesArrives next day




20h 6m • 4 changes



11h 49m • 4 changes



11h 33m • 4 changes



11h 52m • 4 changes



12h 7m • 4 changes



11h 49m • 4 changes



11h 33m • 4 changes



11h 52m • 4 changes



12h 7m • 4 changes



11h 50m • 4 changes



11h 33m • 4 changes



11h 52m • 4 changes



12h 7m • 4 changes



11h 50m • 4 changes



11h 33m • 4 changes



11h 52m • 4 changes



12h 7m • 4 changes



13h 41m • 4 changes



11h 50m • 4 changes



12h 23m • 4 changes



11h 52m • 4 changes



13h 41m • 4 changes



11h 50m • 4 changes



12h 23m • 4 changes



11h 52m • 4 changesWant to know about travelling from Mainz to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Italy. However, there are services departing from Mainz station and arriving at Italy station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 14h 48m.
Mainz to Italy train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz to Italy train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Roma Termini station.
Book your Mainz to Italy train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 4 other operators.
The distance between Mainz and Italy is 883.4 km. The road distance is 1,232 km.
You can take a train from Mainz, Hauptbahnhof to Roma Termini via Mannheim, Hauptbahnhof, Basel SBB, Lugano, and Milano Centrale in around 12h 34m.