Mainz to Karlovy Vary Trains

Mainz to Karlovy Vary trains

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Trip Overview

The average train between Mainz and Karlovy Vary takes 7h 18m and the fastest train takes 5h 49m. The train runs, on average, 6 times per week from Mainz to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 18m
Duration: 462 km
Distance: Kč 2,253
Average price: 6 times a week
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Nürnberg Hbftrain 91 / ...
Take the train from Nürnberg Hbf to Chebtrain
Take the train from Cheb to Karlovy Varytrain Re / ...

6h 31m

Kč 1,877–5,348

Mainz to Karlovy Vary train times

Trains run 6 times a week between Mainz and Karlovy Vary. The earliest departure is at 7:40 AM in the morning, and the last departure from Mainz is at 9:44 PM which arrives into Karlovy Vary at 11:31 AM. All services require a transfer at Nürnberg Hbf and take an average of 7h 18m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

9:44 PM → 11:31 AM
Arrives next day
13h 47m • 2 changes

Departing Saturday, October 31, 2026

7:40 AM → 2:22 PM
6h 42m • 2 changes
9:42 AM → 3:31 PM
5h 49m • 2 changes
11:42 AM → 5:31 PM
5h 49m • 2 changes
1:42 PM → 7:31 PM
5h 49m • 2 changes
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Frequently asked questions

Want to know about travelling from Mainz to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.