The average train between Mainz and Leipzig takes 5h 19m and the fastest train takes 3h 50m. The train service runs several times per day from Mainz to Leipzig. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mainz and Leipzig. The earliest departure is at 5:09 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Leipzig at 9:09 AM. All services require a transfer at Frankfurt and take an average of 5h 19m. The schedules shown below are for the next available departures.


4h 55m • 2 changes


3h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 55m • 2 changes


3h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 55m • 2 changes


3h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 55m • 2 changes


3h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 50m • 2 changes


4h 47m • 2 changes


4h 50m • 2 changes
Want to know about travelling from Mainz to Leipzig? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Leipzig. However, there are services departing from Mainz station and arriving at Leipzig station via Erfurt Hbf. The journey, including transfers, takes approximately 5h 19m.
Mainz to Leipzig train services, operated by vlexx, depart from Frankfurt station.
Mainz to Leipzig train services, operated by vlexx, arrive at Leipzig Hbf station.
Book your Mainz to Leipzig train tickets online with vlexx and Deutsche Bahn Intercity (DB IC).
The distance between Mainz and Leipzig is 325.4 km. The road distance is 409 km.
You can take a train from Mainz, Römisches Theater to Leipzig Hbf via Frankfurt and Erfurt Hbf in around 4h 18m.