The average train between Mainz and Luxembourg takes 4h 7m and the fastest train takes 3h 38m. There is a train service every few hours from Mainz to Luxembourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Luxembourg. The earliest departure is at 3:49 AM at night, and the last departure from Mainz is at 5:51 PM which arrives into Luxembourg at 9:29 PM. All services require a transfer at Koblenz Hauptbahnhof and take an average of 4h 7m. The schedules shown below are for the next available departures.


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Want to know about travelling from Mainz to Luxembourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Luxembourg. However, there are services departing from Mainz station and arriving at Luxembourg station via Koblenz Hauptbahnhof. The journey, including transfers, takes approximately 4h 7m.
Mainz to Luxembourg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz to Luxembourg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Luxembourg station.
Book your Mainz to Luxembourg train tickets online with Deutsche Bahn Intercity (DB IC), Luxembourg Railways (CFL) and 3 other operators.
The distance between Mainz and Luxembourg is 159.7 km. The road distance is 253 km.
You can take a train from Mainz, Hauptbahnhof to Luxembourg via Koblenz Hauptbahnhof and Trier, Hauptbahnhof in around 3h 53m.