Mainz to Milan Cathedral Trains

Mainz to Milan Cathedral trains

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Trip Overview

The average train between Mainz and Milan Cathedral takes 9h 49m and the fastest train takes 7h 48m. The train service runs several times per day from Mainz to Milan Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 49m
Duration: 655 km
Distance: €154
Average price: 5 times a day
Frequency

Train

best

Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain

9h 30m

€62–267

Mainz to Milan Cathedral train times

Trains run 5 times a day between Mainz and Milan Cathedral. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Milan Cathedral at 11:29 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 9h 49m. The schedules shown below are for the next available departures.

Departing Thursday, October 15, 2026

4:53 PM → 7:28 AM
Arrives next day
14h 35m • 4 changes
11:08 PM → 11:29 AM
Arrives next day
12h 21m • 4 changes

Departing Friday, October 16, 2026

5:40 AM → 1:34 PM
7h 54m • 4 changes
7:46 AM → 3:34 PM
7h 48m • 4 changes
9:13 AM → 5:31 PM
8h 18m • 4 changes
11:17 AM → 7:26 PM
8h 9m • 4 changes
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Departing Saturday, October 17, 2026

1:38 AM → 11:32 AM
9h 54m • 4 changes
5:40 AM → 1:33 PM
7h 53m • 4 changes
6:56 AM → 3:34 PM
8h 38m • 4 changes
9:13 AM → 5:35 PM
8h 22m • 4 changes
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Departing Sunday, October 18, 2026

1:38 AM → 11:31 AM
9h 53m • 4 changes
5:40 AM → 1:34 PM
7h 54m • 4 changes
6:56 AM → 3:33 PM
8h 37m • 4 changes
9:13 AM → 5:32 PM
8h 19m • 4 changes
Show more

Departing Monday, October 19, 2026

5:40 AM → 1:34 PM
7h 54m • 4 changes
7:46 AM → 3:34 PM
7h 48m • 4 changes
9:13 AM → 5:31 PM
8h 18m • 4 changes
11:17 AM → 7:26 PM
8h 9m • 4 changes
Show more

Frequently asked questions

Want to know about travelling from Mainz to Milan Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Mainz, Germany and Milan Cathedral, Lombardy, Italy?

You can take a train from Mainz, Hauptbahnhof to Milan Cathedral via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, Centrale Fs, and Duomo M3 in around 9h 30m.

Operators