The average train between Mainz and Milan Cathedral takes 9h 52m and the fastest train takes 7h 43m. The train service runs several times per day from Mainz to Milan Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Milan Cathedral. The earliest departure is at 1:38 AM at night, and the last departure from Mainz is at 11:08 PM which arrives into Milan Cathedral at 11:39 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 9h 52m. The schedules shown below are for the next available departures.




7h 54m • 4 changes



7h 43m • 4 changes



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10h • 4 changes



7h 53m • 4 changes



8h 33m • 4 changes



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10h 1m • 4 changes



7h 54m • 4 changes



8h 31m • 4 changes



8h 19m • 4 changes



7h 54m • 4 changes



7h 43m • 4 changes



8h 18m • 4 changes



8h 16m • 4 changes



7h 54m • 4 changes



7h 43m • 4 changes



8h 18m • 4 changes



8h 16m • 4 changes



7h 54m • 4 changes



7h 43m • 4 changes



8h 18m • 4 changes



8h 16m • 4 changes



7h 54m • 4 changes



7h 43m • 4 changes



8h 18m • 4 changes



8h 16m • 4 changesWant to know about travelling from Mainz to Milan Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Milan Cathedral. However, there are services departing from Mainz station and arriving at Milan Cathedral station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 9h 52m.
Mainz to Milan Cathedral train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz to Milan Cathedral train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Milano Centrale station.
The distance between Mainz and Milan Cathedral is 507.2 km. The road distance is 655 km.
You can take a train from Mainz, Hauptbahnhof to Milan Cathedral via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, Centrale Fs, and Duomo M3 in around 9h 30m.