Mainz to Pisa trains

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Trip Overview

The average train between Mainz and Pisa takes 15h 53m and the fastest train takes 12h 14m. The train service runs several times per day from Mainz to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 53m
Duration: 1,062 km
Distance: €260
Average price: Every 4 hours
Frequency

Train

best

Take the train from Frankfurt to Basel SBBtrain 43
Take the train from Basel SBB to Luganotrain Ec
Take the train from Lugano to Milano Centraletrain
Take the train from Milano Centrale to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Pisa Centraletrain Re

13h 53m

€127–433

Mainz to Pisa train times

Trains run every 4 hours between Mainz and Pisa. The earliest departure is at 7:05 AM in the morning, and the last departure from Mainz is at 7:14 PM which arrives into Pisa at 3:28 PM. All services require a transfer at Frankfurt and take an average of 15h 53m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

7:05 AM → 7:28 PM
12h 23m • 5 changes
9:14 AM → 9:59 PM
12h 45m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Monday, November 2, 2026

7:13 AM → 7:28 PM
12h 15m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Tuesday, November 3, 2026

7:13 AM → 7:28 PM
12h 15m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Wednesday, November 4, 2026

7:13 AM → 7:28 PM
12h 15m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Thursday, November 5, 2026

7:13 AM → 7:28 PM
12h 15m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Friday, November 6, 2026

7:13 AM → 7:28 PM
12h 15m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes
1:14 PM → 8:28 AM
Arrives next day
19h 14m • 5 changes
Show more

Departing Saturday, November 7, 2026

7:05 AM → 7:28 PM
12h 23m • 5 changes
9:14 AM → 9:28 PM
12h 14m • 5 changes
11:14 AM → 12:29 AM
Arrives next day
13h 15m • 5 changes

Frequently asked questions

Want to know about travelling from Mainz to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Launch map view

Distance: 1,062.3 km
Duration: 15h 53m

What companies run services between Mainz, Germany and Pisa, Italy?

You can take a train from Mainz, Römisches Theater to Pisa Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 53m.

Operators