The average train between Mainz and Tuscany takes 14h 51m and the fastest train takes 10h 21m. The train service runs several times per day from Mainz to Tuscany. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Mainz and Tuscany. The earliest departure is at 7:05 AM in the morning, and the last departure from Mainz is at 7:14 PM which arrives into Tuscany at 2:35 PM. All services require a transfer at Frankfurt and take an average of 14h 51m. The schedules shown below are for the next available departures.




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16h 21m • 4 changesWant to know about travelling from Mainz to Tuscany? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Tuscany. However, there are services departing from Frankfurt station and arriving at Firenze Santa Maria Novella station via Basel SBB station, Lugano station and Milano Centrale station. The journey, including transfers, takes approximately 14h 51m.
Mainz to Tuscany train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Mainz to Tuscany train services, operated by ItaloTreno, arrive at Firenze Santa Maria Novella station.
The distance between Mainz and Tuscany is 757.5 km. The road distance is 958 km.
You can take a train from Mainz, Römisches Theater to Firenze Santa Maria Novella via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 12h 17m.