The average train between Mainz and Zürich HB takes 4h 57m and the fastest train takes 4h 14m. There is a train service every few hours from Mainz to Zürich HB. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mainz and Zürich HB. The earliest departure is at 5:40 AM in the morning, and the last departure from Mainz is at 11:08 PM which arrives into Zürich HB at 7:26 AM. All services require a transfer at Mannheim, Hauptbahnhof and take an average of 4h 57m. The schedules shown below are for the next available departures.


4h 20m • 2 changes


5h 32m • 2 changes


4h 14m • 2 changes


4h 42m • 2 changes


4h 20m • 2 changes


5h 32m • 2 changes


4h 14m • 2 changes


4h 42m • 2 changes


4h 20m • 2 changes


5h 32m • 2 changes


4h 14m • 2 changes


4h 42m • 2 changes
Want to know about travelling from Mainz to Zürich HB? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Zürich HB. However, there are services departing from Mainz station and arriving at Zürich HB station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 4h 57m.
Mainz to Zürich HB train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
Mainz to Zürich HB train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Zürich HB station.
Book your Mainz to Zürich HB train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 3 other operators.
The distance between Mainz and Zürich HB is 290.4 km. The road distance is 411 km.
You can take a train from Mainz, Hauptbahnhof to Zürich HB via Mannheim, Hauptbahnhof and Basel SBB in around 4h 45m.