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Manchester Piccadilly Station to Middlesex trains

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Trip Overview

The average train between Manchester Piccadilly Station and Middlesex takes 2h 44m and the fastest train takes 2h 23m. The train runs at least 2 times per hour from Manchester Piccadilly Station to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 44m
Duration
188 mi
Distance
£79
Average price
Every 30 minutes
Frequency

Manchester Piccadilly Station to Middlesex train times

Trains run every 30 minutes between Manchester Piccadilly Station and Middlesex. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester Piccadilly Station is at 10:15 PM which arrives into Middlesex at 5:51 AM. All services require a transfer, and take on average 2h 44m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

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    Avanti West CoastLondon Overground3h 8m • 1 change
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    Avanti West CoastLondon Overground3h 8m • 1 change
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    Avanti West CoastLondon Overground3h 23m • 1 change
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    Avanti West CoastLondon Overground2h 53m • 1 change
  • Show more

Departing Monday, October 26, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
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    Avanti West CoastLondon Overground2h 33m • 1 change
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    Avanti West CoastLondon Overground2h 28m • 1 change
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    Avanti West CoastLondon Overground2h 43m • 1 change
  • Show more

Departing Tuesday, October 27, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
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    Avanti West CoastLondon Overground2h 33m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 28m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 43m • 1 change
  • Show more

Departing Wednesday, October 28, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
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    Avanti West CoastLondon Overground2h 33m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 28m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 43m • 1 change
  • Show more

Departing Thursday, October 29, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
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    Avanti West CoastLondon Overground2h 33m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 28m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 43m • 1 change
  • Show more

Departing Friday, October 30, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 33m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 28m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 43m • 1 change
  • Show more

Departing Saturday, October 31, 2026

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    Avanti West CoastLondon Overground2h 53m • 1 change
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    Avanti West CoastLondon Overground2h 32m • 1 change
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    Avanti West CoastLondon Overground2h 27m • 1 change
  •  → 

    Avanti West CoastLondon Overground2h 33m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Manchester Piccadilly Station to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester Piccadilly Station to Middlesex.ExpandLaunch map view
  • Distance: 188 mi
  • Duration: 2h 44m

What companies run services between Manchester Piccadilly Station, England and Middlesex, England?

Avanti West Coast operates a train from Manchester Piccadilly to London Euston every 30 minutes. Tickets cost £60–100 and the journey takes 2h 8m.

Operators