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Manchester Piccadilly Station to Milan trains

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Trip Overview

The average train between Manchester Piccadilly Station and Milan takes 17h 18m and the fastest train takes 12h 32m. The train service runs several times per day from Manchester Piccadilly Station to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 18m
Duration
1,649 km
Distance
€422
Average price
Twice daily
Frequency

Manchester Piccadilly Station to Milan train times

Trains run twice daily between Manchester Piccadilly Station and Milan. The earliest departure is at 8:05 AM in the morning, and the last departure from Manchester Piccadilly Station is at 5:15 PM which arrives into Milan at 2:07 PM. All services require a transfer at London Euston and take an average of 17h 18m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia13h 2m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia24h 15m • 3 changes

Departing Monday, November 9, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia24h 15m • 3 changes

Departing Tuesday, November 10, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia19h 52m • 3 changes

Departing Wednesday, November 11, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia24h 15m • 3 changes

Departing Thursday, November 12, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia24h 15m • 3 changes

Departing Friday, November 13, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes
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    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitalia19h 52m • 3 changes

Departing Saturday, November 14, 2026

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    Avanti West CoastEurostarTGV inOuiTrenitalia12h 32m • 3 changes

Frequently asked questions

Want to know about travelling from Manchester Piccadilly Station to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester Piccadilly Station to Milan.ExpandLaunch map view
  • Distance: 1,648.9 km
  • Duration: 17h 18m

What companies run services between Manchester Piccadilly Station, England and Milan, Italy?

You can take a train from Manchester Piccadilly to Milano Centrale via London Euston, London St Pancras Intl, Lille Europe, and Lyon Part Dieu in around 14h 27m.

Operators