The average train between Manchester Piccadilly Station and Rome takes 25h 7m and the fastest train takes 22h 55m. The train service runs several times per day from Manchester Piccadilly Station to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Manchester Piccadilly Station and Rome. The earliest departure is at 8:15 AM in the morning, and the last departure from Manchester Piccadilly Station is at 8:15 PM which arrives into Rome at 9:24 AM. All services require a transfer at London Euston and take an average of 25h 7m. The schedules shown below are for the next available departures.
Arrives next day




25h 9m • 4 changes
Arrives next day




23h 55m • 4 changes
Arrives next day




25h 9m • 4 changes
Arrives next day




23h 55m • 4 changes
Want to know about travelling from Manchester Piccadilly Station to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester Piccadilly Station to Rome. However, there are services departing from Manchester Piccadilly Station station and arriving at Rome station via London Euston. The journey, including transfers, takes approximately 25h 7m.
Manchester Piccadilly Station to Rome train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester Piccadilly Station to Rome train services, operated by Avanti West Coast, arrive at Roma Termini station.
Book your Manchester Piccadilly Station to Rome train tickets online with Avanti West Coast, Eurostar and 3 other operators.
The distance between Manchester Piccadilly Station and Rome is 1,688.2 km. The road distance is 2,230 km.
You can take a train from Manchester Piccadilly to Roma Termini via London Euston, London St Pancras Intl, Lille Europe, Lyon Part Dieu, and Milano Centrale in around 17h 16m.