The average train between Manchester and Denham takes 3h 26m and the fastest train takes 2h 48m. There is an hourly train service from Manchester to Denham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Manchester and Denham. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester is at 8:56 PM which arrives into Denham at 6:34 AM. All services require a transfer at London Euston and take an average of 3h 26m. The schedules shown below are for the next available departures.



3h 8m • 3 changes



2h 54m • 3 changes



3h 28m • 3 changes



3h 34m • 3 changes



4h 2m • 3 changes



4h 1m • 3 changes



3h 6m • 3 changes



2h 56m • 3 changes



3h 32m • 3 changes



2h 48m • 3 changes



3h 4m • 3 changes



3h 1m • 3 changes
Want to know about travelling from Manchester to Denham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Denham. However, there are services departing from Manchester station and arriving at Denham station via London Euston. The journey, including transfers, takes approximately 3h 26m.
Manchester to Denham train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Denham train services, operated by Avanti West Coast, arrive at London Euston station.
Book your Manchester to Denham train tickets online with Avanti West Coast, London Underground (Tube) and Chiltern Railways.
The distance between Manchester and Denham is 242.5 km. The road distance is 324 km.
Avanti West Coast operates a train from Manchester Piccadilly to London Euston every 30 minutes. Tickets cost £65–110 and the journey takes 2h 7m.