The average train between Manchester and Gretna takes 2h 42m and the fastest train takes 2h 6m. The train service runs several times per day from Manchester to Gretna. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Manchester and Gretna. The earliest departure is at 4:57 AM at night, and the last departure from Manchester is at 8:21 PM which arrives into Gretna at 11:21 PM. All services require a transfer, and take on average 2h 42m. The schedules shown below are for the next available departures.

2h 59m • 1 change

2h 59m • 1 change

2h 17m • 1 change

2h 14m • 1 change

2h 15m • 1 change

2h 43m • 1 change

2h 44m • 1 change

3h 3m • 1 change

2h 15m • 1 change

2h 43m • 1 change

2h 44m • 1 change

3h 3m • 1 change

2h 15m • 1 change

2h 43m • 1 change

2h 44m • 1 change

3h 3m • 1 change

2h 15m • 1 change

2h 43m • 1 change

2h 44m • 1 change

3h 3m • 1 change
Want to know about travelling from Manchester to Gretna? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Gretna. However, there are services departing from Manchester station and arriving at Gretna station via Carlisle. The journey, including transfers, takes approximately 2h 42m.
Manchester to Gretna train services, operated by TransPennine Express, depart from Manchester Piccadilly station.
Manchester to Gretna train services, operated by TransPennine Express, arrive at Carlisle station.
Book your Manchester to Gretna train tickets online with TransPennine Express and ScotRail.
The distance between Manchester and Gretna is 176.8 km. The road distance is 210 km.
TransPennine Express operates a train from Manchester Piccadilly to Carlisle hourly. Tickets cost £40–75 and the journey takes 1h 55m.