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Manchester to Isola Ortigia trains

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Trip Overview

The average train between Manchester and Isola Ortigia takes 37h 18m and the fastest train takes 37h 3m. The train runs, on average, 2 times per week from Manchester to Isola Ortigia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h 18m
Duration
3,050 km
Distance
€592
Average price
Twice a week
Frequency

Manchester to Isola Ortigia train times

Trains run twice a week between Manchester and Isola Ortigia. The earliest departure is at 8:05 AM in the morning, and the last departure from Manchester is at 8:35 AM which arrives into Isola Ortigia at 10:38 PM. All services require a transfer at London Euston and take an average of 37h 18m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 33m • 5 changes

Departing Monday, October 19, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 3m • 5 changes

Frequently asked questions

Want to know about travelling from Manchester to Isola Ortigia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Isola Ortigia.ExpandLaunch map view
  • Distance: 3,050.5 km
  • Duration: 37h 18m

What companies run services between Manchester, England and Isola Ortigia, Italy?

You can take a train from Manchester Piccadilly to Siracusa via London Euston, London St Pancras Intl, Lille Europe, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 29h 39m.

Operators