The average train between Manduria and Mesagne takes 5h 12m and the fastest train takes 1h 44m. The train service runs several times per day from Manduria to Mesagne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Manduria and Mesagne. The earliest departure is at 9:55 AM in the morning, and the last departure from Manduria is at 6:47 PM which arrives into Mesagne at 6:17 AM. All services require a transfer, and take on average 5h 12m. The schedules shown below are for the next available departures.

3h 39m • 1 change

1h 44m • 1 change
Arrives next day

11h 30m • 1 change

3h 39m • 1 change

1h 44m • 1 change
Arrives next day

11h 30m • 1 change

3h 39m • 1 change

1h 44m • 1 change
Arrives next day

11h 30m • 1 change
Want to know about travelling from Manduria to Mesagne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manduria to Mesagne. However, there are services departing from Manduria station and arriving at Mesagne station via Francavilla Fontana. The journey, including transfers, takes approximately 5h 12m.
Manduria to Mesagne train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Manduria station.
Manduria to Mesagne train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Mesagne station.
Book your Manduria to Mesagne train tickets online with Ferrovie del Sud Est e Servizi Automobilistici S.r.l. and Trenitalia.
The distance between Manduria and Mesagne is 22.9 km. The road distance is 36 km.
You can take a train from Manduria to Mesagne via Francavilla Fontana in around 1h 34m.