The average train between Manfredonia and Brindisi takes 3h 43m and the fastest train takes 2h 47m. The train service runs several times per day from Manfredonia to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manfredonia and Brindisi. The earliest departure is at 7:38 AM in the morning, and the last departure from Manfredonia is at 6:42 PM which arrives into Brindisi at 9:29 PM. All services require a transfer, and take on average 3h 43m. The schedules shown below are for the next available departures.

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change

3h 47m • 1 change

4h 11m • 1 change

3h 52m • 1 change

4h 36m • 1 change
Want to know about travelling from Manfredonia to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manfredonia to Brindisi. However, there are services departing from Manfredonia station and arriving at Brindisi station via Brindisi. The journey, including transfers, takes approximately 3h 43m.
Manfredonia to Brindisi train services, operated by Trenitalia, depart from Foggia station.
Manfredonia to Brindisi train services, operated by Trenitalia, arrive at Brindisi station.
Book your Manfredonia to Brindisi train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Manfredonia and Brindisi is 202.2 km. The road distance is 269 km.
Trenitalia Frecce operates a train from Foggia to Brindisi hourly. Tickets cost €35–70 and the journey takes 2h 6m. Trenitalia Intercity also services this route every 3 hours.