The average train between Manhattan and Medford takes 4h 29m and the fastest train takes 3h 59m. There is a train service every few hours from Manhattan to Medford. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Manhattan and Medford. The earliest departure is at 5:27 AM in the morning, and the last departure from Manhattan is at 7:50 PM which arrives into Medford at 12:34 AM. All services require a transfer at Boston and take an average of 4h 29m. The schedules shown below are for the next available departures.

4h 20m • 1 change

4h 34m • 1 change

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4h 26m • 1 change

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4h 26m • 1 change

4h 20m • 1 change

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4h 19m • 1 change

4h 26m • 1 change

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4h 34m • 1 change

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4h 26m • 1 change
Want to know about travelling from Manhattan to Medford? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manhattan to Medford. However, there are services departing from Manhattan station and arriving at Medford station via Boston. The journey, including transfers, takes approximately 4h 29m.
Manhattan to Medford train services, operated by Amtrak Acela, depart from Ny Moynihan Train Hall At Penn Station.
Manhattan to Medford train services, operated by Amtrak Acela, arrive at Boston station.
The distance between Manhattan and Medford is 299.3 km. The road distance is 378 km.
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 36m. Amtrak also services this route every 3 hours.