The average train between Mannheim Central Station and Prague takes 9h 11m and the fastest train takes 8h 18m. The train service runs several times per day from Mannheim Central Station to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mannheim Central Station and Prague. The earliest departure is at 4:01 AM at night, and the last departure from Mannheim Central Station is at 8:03 PM which arrives into Prague at 10:21 AM. All services require a transfer at Frankfurt and take an average of 9h 11m. The schedules shown below are for the next available departures.



8h 18m • 3 changes



8h 18m • 3 changes



8h 19m • 3 changes
Arrives next day



14h 18m • 3 changes



8h 20m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 20m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 20m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 20m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 20m • 3 changes



8h 49m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 20m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes



8h 18m • 3 changes
Want to know about travelling from Mannheim Central Station to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim Central Station to Prague. However, there are services departing from Mannheim Central Station station and arriving at Prague station via Frankfurt. The journey, including transfers, takes approximately 9h 11m.
Mannheim Central Station to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim Central Station to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Praha Hlavni Nadrazi station.
Book your Mannheim Central Station to Prague train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Die Länderbahn.
The distance between Mannheim Central Station and Prague is 432.5 km. The road distance is 642 km.
You can take a train from Mannheim, Hauptbahnhof to Praha Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 9h 28m.