The average train between Mannheim, Hauptbahnhof and Brussels takes 4h 2m and the fastest train takes 3h 31m. The train service runs several times per day from Mannheim, Hauptbahnhof to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mannheim, Hauptbahnhof and Brussels. The earliest departure is at 4:01 AM at night, and the last departure from Mannheim, Hauptbahnhof is at 7:33 PM which arrives into Brussels at 11:26 PM. All services require a transfer, and take on average 4h 2m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mannheim, Hauptbahnhof to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim, Hauptbahnhof to Brussels. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Brussels station via Frankfurt. The journey, including transfers, takes approximately 4h 2m.
Mannheim, Hauptbahnhof to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim, Hauptbahnhof to Brussels train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Brussels-Nord station.
Book your Mannheim, Hauptbahnhof to Brussels train tickets online with Deutsche Bahn Intercity (DB IC).
The distance between Mannheim, Hauptbahnhof and Brussels is 330.7 km. The road distance is 456 km.
You can take a train from Mannheim, Hauptbahnhof to Brussels-Nord via Frankfurt in around 4h 26m.