The average train between Mannheim and Brindisi takes 20h 47m and the fastest train takes 15h 55m. The train service runs several times per day from Mannheim to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mannheim and Brindisi. The earliest departure is at 3:31 AM at night, and the last departure from Mannheim is at 6:37 PM which arrives into Brindisi at 6:24 PM. All services require a transfer at Basel SBB and take an average of 20h 47m. The schedules shown below are for the next available departures.




17h 3m • 4 changes




15h 55m • 4 changes
Arrives next day




25h 28m • 4 changes
Arrives next day




23h 47m • 4 changes




17h 3m • 4 changes




15h 55m • 4 changes
Arrives next day




25h 28m • 4 changes
Arrives next day




23h 47m • 4 changes
Want to know about travelling from Mannheim to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Brindisi. However, there are services departing from Mannheim station and arriving at Brindisi station via Basel SBB. The journey, including transfers, takes approximately 20h 47m.
Mannheim to Brindisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Brindisi train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Brindisi station.
Book your Mannheim to Brindisi train tickets online with Deutsche Bahn Intercity (DB IC), Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Mannheim and Brindisi is 1,232.1 km. The road distance is 1,551 km.
You can take a train from Mannheim, Hauptbahnhof to Brindisi via Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 17h 9m.