The average train between Mannheim and Dessau takes 5h 6m and the fastest train takes 4h 30m. The train service runs several times per day from Mannheim to Dessau. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Mannheim and Dessau. The earliest departure is at 7:29 AM in the morning, and the last departure from Mannheim is at 11:42 PM which arrives into Dessau at 5:59 AM. All services require a transfer, and take on average 5h 6m. The schedules shown below are for the next available departures.

4h 30m • 1 change

4h 30m • 1 change

4h 30m • 1 change
Arrives next day

6h 17m • 1 change

4h 30m • 1 change

4h 30m • 1 change

4h 30m • 1 change
Arrives next day

6h 17m • 1 change

4h 30m • 1 change

4h 30m • 1 change

4h 30m • 1 change
Arrives next day

6h 17m • 1 change

4h 30m • 1 change

4h 30m • 1 change

4h 30m • 1 change
Arrives next day

6h 17m • 1 change
Want to know about travelling from Mannheim to Dessau? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Dessau. However, there are services departing from Mannheim station and arriving at Dessau station via Leipzig Hbf. The journey, including transfers, takes approximately 5h 6m.
Mannheim to Dessau train services, operated by Österreichische Bundesbahnen, depart from Mannheim, Hauptbahnhof station.
Mannheim to Dessau train services, operated by Österreichische Bundesbahnen, arrive at Dessau Hbf station.
Book your Mannheim to Dessau train tickets online with Österreichische Bundesbahnen, Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Mannheim and Dessau is 373 km. The road distance is 509 km.
You can take a train from Mannheim, Hauptbahnhof to Dessau Hbf via Leipzig Hbf in around 4h 52m.