The average train between Mannheim and Lucerne takes 3h 40m and the fastest train takes 3h 28m. There is a train service every few hours from Mannheim to Lucerne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mannheim and Lucerne. The earliest departure is at 6:37 AM in the morning, and the last departure from Mannheim is at 11:00 PM which arrives into Lucerne at 7:05 AM. All services require a transfer, and take on average 3h 40m. The schedules shown below are for the next available departures.

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3h 28m • 1 changeWant to know about travelling from Mannheim to Lucerne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Lucerne. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Luzern station via Basel SBB station. The journey, including transfers, takes approximately 3h 40m.
Mannheim to Lucerne train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Lucerne train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Luzern station.
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The distance between Mannheim and Lucerne is 271.4 km. The road distance is 350 km.
You can take a train from Mannheim, Hauptbahnhof to Luzern via Basel SBB in around 3h 51m.