The average train between Mannheim and Würzburg takes 2h 48m and the fastest train takes 2h 41m. There is a train service every few hours from Mannheim to Würzburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mannheim and Würzburg. The earliest departure is at 2:15 AM at night, and the last departure from Mannheim is at 7:03 PM which arrives into Würzburg at 9:46 PM. All services require a transfer, and take on average 2h 48m. The schedules shown below are for the next available departures.

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2h 42m • 1 changeWant to know about travelling from Mannheim to Würzburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Würzburg. However, there are services departing from Mannheim, Hauptbahnhof station and arriving at Würzburg Hbf station via Frankfurt station. The journey, including transfers, takes approximately 2h 48m.
Mannheim to Würzburg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Würzburg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Würzburg Hbf station.
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The distance between Mannheim and Würzburg is 112.1 km. The road distance is 147 km.
You can take a train from Mannheim, Hauptbahnhof to Würzburg Hbf via Frankfurt in around 1h 58m.