The average train between Marche and Milan takes 3h 59m and the fastest train takes 3h 55m. The train service runs several times per day from Marche to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Marche and Milan. The earliest departure is at 6:15 AM in the morning, and the last departure from Marche is at 8:25 PM which arrives into Milan at 12:20 AM. All services require a transfer, and take on average 3h 59m. The schedules shown below are for the next available departures.

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Want to know about travelling from Marche to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Marche to Milan. However, there are services departing from Marche station and arriving at Milan station via Reggio Emilia Av. The journey, including transfers, takes approximately 3h 59m.
Marche to Milan train services, operated by Trenitalia Frecce, depart from Ancona station.
Marche to Milan train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
Book your Marche to Milan train tickets online with Trenitalia Frecce.
The distance between Marche and Milan is 392.4 km. The road distance is 417 km.
You can take a train from Ancona to Milano Centrale via Reggio Emilia Av in around 3h 19m.