The average train between Mayen and Frankfurt am Main takes 3h 23m and the fastest train takes 2h 17m. The train service runs several times per day from Mayen to Frankfurt am Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mayen and Frankfurt am Main. The earliest departure is at 5:16 AM in the morning, and the last departure from Mayen is at 10:16 PM which arrives into Frankfurt am Main at 7:03 AM. All services require a transfer at Andernach and take an average of 3h 23m. The schedules shown below are for the next available departures.


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Want to know about travelling from Mayen to Frankfurt am Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mayen to Frankfurt am Main. However, there are services departing from Mayen station and arriving at Frankfurt am Main station via Andernach Bahnhof. The journey, including transfers, takes approximately 3h 23m.
Mayen to Frankfurt am Main train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mayen Ostbahnhof station.
Mayen to Frankfurt am Main train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt station.
Book your Mayen to Frankfurt am Main train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Mayen and Frankfurt am Main is 106.6 km. The road distance is 161 km.
You can take a train from Mayen Ostbahnhof to Frankfurt via Andernach, Koblenz Hbf, and Koblenz Hauptbahnhof in around 3h 16m.