The average train between Mazzeo and Palermo takes 5h 25m and the fastest train takes 4h 10m. The train service runs several times per day from Mazzeo to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mazzeo and Palermo. The earliest departure is at 6:15 AM in the morning, and the last departure from Mazzeo is at 10:17 PM which arrives into Palermo at 7:53 AM. All services require a transfer, and take on average 5h 25m. The schedules shown below are for the next available departures.

4h 15m • 1 change

4h 44m • 1 change

5h 31m • 1 change

4h 10m • 1 change

4h 15m • 1 change

4h 44m • 1 change

5h 31m • 1 change

4h 10m • 1 change

4h 15m • 1 change

4h 44m • 1 change

5h 31m • 1 change

4h 10m • 1 change

4h 15m • 1 change

4h 44m • 1 change

5h 31m • 1 change

4h 10m • 1 change
Want to know about travelling from Mazzeo to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mazzeo to Palermo. However, there are services departing from Mazzeo station and arriving at Palermo station via Messina Centrale. The journey, including transfers, takes approximately 5h 25m.
Mazzeo to Palermo train services, operated by Trenitalia, depart from Letojanni station.
Mazzeo to Palermo train services, operated by Trenitalia, arrive at Palermo Centrale station.
Book your Mazzeo to Palermo train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Mazzeo and Palermo is 174.6 km. The road distance is 263 km.
You can take a train from Letojanni to Palermo Centrale via Messina Centrale in around 4h 38m.