The average train between Medford and Manhattan takes 4h 32m and the fastest train takes 3h 57m. There is a train service every few hours from Medford to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Medford and Manhattan. The earliest departure is at 12:34 AM at night, and the last departure from Medford is at 7:30 PM which arrives into Manhattan at 11:49 PM. All services require a transfer at Back Bay and take an average of 4h 32m. The schedules shown below are for the next available departures.

7h 46m • 1 change

4h 29m • 1 change

4h 9m • 1 change

4h 29m • 1 change

8h 17m • 1 change

4h 29m • 1 change

4h 9m • 1 change

4h 29m • 1 change

8h 17m • 1 change

4h 29m • 1 change

4h 9m • 1 change

4h 29m • 1 change
Want to know about travelling from Medford to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Medford to Manhattan. However, there are services departing from Medford station and arriving at Manhattan station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 4h 32m.
Medford to Manhattan train services, operated by MBTA, depart from Boston station.
Medford to Manhattan train services, operated by MBTA, arrive at Ny Moynihan Train Hall At Penn Station.
The distance between Medford and Manhattan is 299.3 km. The road distance is 378 km.
Amtrak operates a train from Boston to Ny Moynihan Train Hall At Penn Station every 3 hours. Tickets cost $75–160 and the journey takes 3h 57m. Amtrak Acela also services this route every 4 hours.