The average train between Medzilaborce and Prague takes 13h 22m and the fastest train takes 12h. The train service runs several times per day from Medzilaborce to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Medzilaborce and Prague. The earliest departure is at 4:18 AM at night, and the last departure from Medzilaborce is at 8:18 PM which arrives into Prague at 12:18 PM. All services require a transfer at Humenne and take an average of 13h 22m. The schedules shown below are for the next available departures.


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13h 28m • 2 changes
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16h • 2 changes
Want to know about travelling from Medzilaborce to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Medzilaborce to Prague. However, there are services departing from Medzilaborce station and arriving at Prague station via Humenne. The journey, including transfers, takes approximately 13h 22m.
Medzilaborce to Prague train services, operated by Railways of Slovak Republic (ZSSK), depart from Medzilaborce Mesto station.
Medzilaborce to Prague train services, operated by Railways of Slovak Republic (ZSSK), arrive at Praha Hlavni Nadrazi station.
Book your Medzilaborce to Prague train tickets online with Railways of Slovak Republic (ZSSK) and RegioJet.
The distance between Medzilaborce and Prague is 545.8 km. The road distance is 837 km.
You can take a train from Medzilaborce Mesto to Praha Hlavni Nadrazi via Humenne and Kosice in around 12h 18m.