The average train between Mendota and St. Louis takes 11h 43m and the fastest train takes 9h 22m. The train service runs several times per day from Mendota to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mendota and St. Louis. The earliest departure is at 8:53 AM in the morning, and the last departure from Mendota is at 8:09 PM which arrives into St. Louis at 12:01 PM. All services require a transfer, and take on average 11h 43m. The schedules shown below are for the next available departures.

10h 32m • 1 change

9h 22m • 1 change
Arrives next day

15h 52m • 1 change

10h 32m • 1 change

9h 22m • 1 change
Arrives next day

15h 52m • 1 change

10h 32m • 1 change

9h 22m • 1 change
Arrives next day

15h 52m • 1 change

10h 32m • 1 change

9h 22m • 1 change
Arrives next day

15h 52m • 1 change
Want to know about travelling from Mendota to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mendota to St. Louis. However, there are services departing from Mendota station and arriving at St. Louis station via Chicago Union Station station. The journey, including transfers, takes approximately 11h 43m.
Mendota to St. Louis train services, operated by Amtrak, depart from Mendota Station.
Mendota to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Book your Mendota to St. Louis train tickets online with Amtrak.
The distance between Mendota and St. Louis is 337.4 km. The road distance is 584 km.
You can take a train from Mendota Station to St. Louis via Chicago Union Station in around 7h 46m.