The average train between Mendrisio and Brussels takes 11h 20m and the fastest train takes 9h 45m. The train service runs several times per day from Mendrisio to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mendrisio and Brussels. The earliest departure is at 5:34 AM in the morning, and the last departure from Mendrisio is at 9:41 PM which arrives into Brussels at 11:26 AM. All services require a transfer at Lugano and take an average of 11h 20m. The schedules shown below are for the next available departures.




9h 52m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 52m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changesArrives next day




13h 45m • 4 changes



9h 52m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 52m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 52m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changes



9h 45m • 4 changesWant to know about travelling from Mendrisio to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mendrisio to Brussels. However, there are services departing from Mendrisio station and arriving at Brussels station via Basel SBB. The journey, including transfers, takes approximately 11h 20m.
Mendrisio to Brussels train services, operated by Trenord, depart from Lugano station.
Mendrisio to Brussels train services, operated by Trenord, arrive at Brussels-Nord station.
Book your Mendrisio to Brussels train tickets online with Trenord, Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Mendrisio and Brussels is 650.9 km. The road distance is 980 km.
You can take a train from Mendrisio to Brussels-Nord via Lugano, Basel SBB, Mannheim, Hauptbahnhof, and Frankfurt in around 11h 14m.